Understanding Lisinopril’s Pharmacokinetics: Half-Life, Clearance, And Excretion
Lisinopril’s half-life is approximately 12 hours, and its elimination half-life is around 24 hours. Its plasma clearance is approximately 50mL/min, and its renal clearance is around 40mL/min, indicating that it is primarily excreted by the kidneys. Lisinopril undergoes minimal hepatic metabolism, with hepatic clearance accounting for less than 10% of its elimination. Pharmacokinetic Properties of …
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